Expression, function and regulation of Evi-1 during embryonic avian development

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00069046" target="_blank" >RIV/00216224:14110/13:00069046 - isvavai.cz</a>

Alternative codes found

RIV/68081766:_____/13:00394981 RIV/67985904:_____/13:00394981 RIV/62157124:16170/13:43871904

Result on the web

<a href="http://dx.doi.org/10.1016/j.gep.2013.06.002" target="_blank" >http://dx.doi.org/10.1016/j.gep.2013.06.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.gep.2013.06.002" target="_blank" >10.1016/j.gep.2013.06.002</a>

Result language

angličtina

Original language name

Expression, function and regulation of Evi-1 during embryonic avian development

Original language description

Ecotropical viral integration site 1 (Evi-1) is a transcription factor essential for vascularisation and cell proliferation during embryonic development. The chimeric transcription factor AML1-EVI-1 is activated in leukaemia where it plays a role as a differentiation block and stimulator of proliferation. Here, we cloned chicken Evi-1 and analysed its expression during embryonic development. There was early expression in the pharyngeal arches, in the brain and intermediate mesoderm of chicken embryos atstage 15. Later at stage 20, Evi-1 mesenchymal expression was concentrated in the second pharyngeal arch, and weaker expression was found in the mandibular and maxillary prominences. Facial expression decreased in intensity during development. Evi-1 expression in the limb was also limited to the mesenchyme with the most prominent expression in the anterior margin. Evi-1 was not detectable in the posterior limb bud.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

<a href="/en/project/GA304%2F09%2F0725" target="_blank" >GA304/09/0725: Signaling pathways contributing to jaw identity</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Gene Expression Patterns

ISSN

1567-133X

e-ISSN

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Volume of the periodical

13

Issue of the periodical within the volume

8

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

11

Pages from-to

343-353

UT code for WoS article

000328595100008

EID of the result in the Scopus database

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