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Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00073699" target="_blank" >RIV/00216224:14110/14:00073699 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.jab.2014.01.002" target="_blank" >http://dx.doi.org/10.1016/j.jab.2014.01.002</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jab.2014.01.002" target="_blank" >10.1016/j.jab.2014.01.002</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780

  • Original language description

    Antibacterial activity of silver nanoparticles is widely known and used. The effect of application of therapeutical ultrasonic field in the presence of silver nanoparticles &lt;100 nm was examined on human ovarian carcinoma cell A2780. The cell's viability was examined by MTT assay and by life-time microscopy. The presence of nanoparticles in the cell was examined by using electron transmission microscopy. Experimental results indicate a significant decrease of viability of cell, which was affected by the combined action of ultrasound field and silver nanoparticles, compared to the separate exposure of silver nanoparticles or ultrasonic field. The experiments showed a significant effect of succession of application of these two factors. The presence ofnanoparticles inside cells after incubation was showed. The results show the possibility of using of ultrasonic field as a factor that can significantly affect cell viability in the presence of silver nanoparticles.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP13-04408P" target="_blank" >GP13-04408P: Effects of combined nanoparticle and ultrasound treatment on carcinoma cells</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Applied Biomedicine

  • ISSN

    1214-021X

  • e-ISSN

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    9

  • Pages from-to

    137-145

  • UT code for WoS article

    000340867600002

  • EID of the result in the Scopus database