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Sentinel lymph node dissection combined with meticulous histology increases the detection rate of nodal metastases in prostate cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00075216" target="_blank" >RIV/00216224:14110/14:00075216 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1007/s11255-014-0704-3" target="_blank" >http://dx.doi.org/10.1007/s11255-014-0704-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s11255-014-0704-3" target="_blank" >10.1007/s11255-014-0704-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sentinel lymph node dissection combined with meticulous histology increases the detection rate of nodal metastases in prostate cancer

  • Original language description

    To evaluate benefits of sentinel lymph node (SLN) biopsy for staging accuracy in prostate cancer. Extended pelvic lymph node dissection (ePLND) is a preferred staging tool; however, it may underestimate the incidence of nodal involvement. Eighty patientswith estimated risk of lymphadenopathy above 5 % based on Briganti nomogram had Tc-99m-labeled nanocolloid injected into the prostate. Planar lymphoscintigraphy and single-photon emission computed tomography/CT were performed to localize SLNs. Radioguided SLN dissection was followed by backup ePLND comprising external iliac, obturator and internal iliac regions. All SLNs were serially sectioned every 150 mu m and examined using hematoxylin and eosin; immunohistochemical staining was applied every 300 mu m. A total of 335 SLNs were detected, and 17 % were located outside ePLND template. Nodal metastases were diagnosed in 32 patients (40 %).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FE - Other fields of internal medicine

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Urology and Nephrology

  • ISSN

    0301-1623

  • e-ISSN

  • Volume of the periodical

    46

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    7

  • Pages from-to

    1543-1549

  • UT code for WoS article

    000340523800012

  • EID of the result in the Scopus database