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Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00075299" target="_blank" >RIV/00216224:14110/14:00075299 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.4172/1948-5956.1000244" target="_blank" >http://dx.doi.org/10.4172/1948-5956.1000244</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4172/1948-5956.1000244" target="_blank" >10.4172/1948-5956.1000244</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer

  • Original language description

    Bone metastases and treatment-induced osteoporosis are frequently the maincauses of morbidity in patients with malignancies. Monitoring the level of bone markers (markers of bone metabolism) has been fairly well mapped in osteoporosis, where medical procedures can be modified according to the kinetics of marker levels before an answer can be evaluated by densitometry and before the onset of fractures. In bone metastases the role of these levels is not clear. The metabolic markers of bone resorption under review in this set were ß-Cross Laps (CTX) - a peptide that is a part of C - telopeptide, and N-terminal propeptide of collagen type 1 (P1NP). Material and methods: We monitored a group of 52 female patients with metastatic breastcancer. The patients received appropriate systemic treatment based on the immunohistochemistry of the tumor; the treatment consisted of hormone therapy or chemotherapy, and included parenteral bisphosphonates (ibandronate and zoledronic acid alternately).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Cancer Science and Therapy

  • ISSN

    1948-5956

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    27-31

  • UT code for WoS article

  • EID of the result in the Scopus database