Adipose Tissue Endocrine Regulations in Metabolic Syndrome and Appetite

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00075512" target="_blank" >RIV/00216224:14110/14:00075512 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Adipose Tissue Endocrine Regulations in Metabolic Syndrome and Appetite
Original language description
The current worldwide epidemic of metabolic syndrome represents an urgent challenge for new pharmacotherapy development. There is growing evidence of multiple metabolic dysregulations contributing to the development of the pathophysiological processes underlying metabolic syndrome. The adipose tissue metabolism and its endocrine activity is one of the key mechanisms believed to provide new targets for pharmacotherapy. The aim of this chapter is to provide a survey on metabolic syndrome pathophysiology,etiology and hypotheses of its development with special attention focused on insulin resistance, inflammatory processes and endocrine activity of the adipose tissue. Specific adipokines secreted by the body fat have multiple effects on the energy metabolism and can either support or suppress insulin signaling. Their pharmacological exploitation may lead to development of new treatments of insulin resistance and metabolic syndrome.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Appetite: Regulation, Use of Stimulants and Cultural and Biological Influences
ISBN
9781631172434
Number of pages of the result
26
Pages from-to
97-122
Number of pages of the book
220
Publisher name
Nova Science Publishers
Place of publication
New York
UT code for WoS chapter
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