CIRCULATING MIR-34a AND MIR-130a AS BIOMARKERS OF EXTRAMEDULLARY DISEASE
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00076659" target="_blank" >RIV/00216224:14110/14:00076659 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
CIRCULATING MIR-34a AND MIR-130a AS BIOMARKERS OF EXTRAMEDULLARY DISEASE
Original language description
MicroRNAs (miRNA), short non-coding regulatory RNAs, are implicated in deregulation of critical pathways involved in multiple myeloma (MM) and extramedullary form of MM (EM). EM is a type of MM defined by the presence of extraskeletal plasma cells (PCs)infiltrates, either related to bone or present in soft tissue. EM Circulating miRNAs are highly stable and are both detectable and quantifiable in a range of accessible bio fluids, thus have the potential to be useful diagnostic biomarkers. We have identified a specific serum miRNA profile in patients with extramedullary disease and correlated it with clinically important parameters.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.20.0046" target="_blank" >EE2.3.20.0046: International centre for research and training in hematooncology and monoclonal gammopathy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů