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Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077147" target="_blank" >RIV/00216224:14110/14:00077147 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/14:00061027

  • Result on the web

    <a href="http://dx.doi.org/10.1259/bjr.20130545" target="_blank" >http://dx.doi.org/10.1259/bjr.20130545</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1259/bjr.20130545" target="_blank" >10.1259/bjr.20130545</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Utility of a rescue endovascular therapy for the treatment of major strokes refractory to full-dose intravenous thrombolysis

  • Original language description

    Objective: Large artery occlusion (LAO) in patients with major stroke predicts poor revascularization by intravenous thrombolysis (IVT) and more likely results in a poor outcome. We focused on the effects of intra- arterial thrombolysis (IAT) and endovascular mechanical recanalization (EMR) as rescue therapies in major strokes refractory to IVT. Methods: A retrospective analysis of 87 patients (National Institutes of Health Stroke Scale &gt;20), who did not respond to full-dose IVT due to LAO, was performed based on their endovascular therapy status. IAT was performed as an intraclot infusion of alteplase, and EMR was provided by the Solitaire device (TM) (Covidien, Dubin, Ireland). The recanalization and 3-month outcome rates after IAT/EMR were correlated with a group of patients who were scheduled to receive endovascular treatment but who underwent only IVT. Results: We achieved successful recanalization by IAT and EMR in 68.7% and 76.1% of patients, respectively.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BRITISH JOURNAL OF RADIOLOGY

  • ISSN

    0007-1285

  • e-ISSN

  • Volume of the periodical

    87

  • Issue of the periodical within the volume

    1036

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    9

  • Pages from-to

    "20130545"

  • UT code for WoS article

    000334291900006

  • EID of the result in the Scopus database