Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture Two-Year Follow-up of a Prospective Randomized Trial
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077193" target="_blank" >RIV/00216224:14110/14:00077193 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/14:#0000304
Result on the web
<a href="http://dx.doi.org/10.1177/0363546514528093" target="_blank" >http://dx.doi.org/10.1177/0363546514528093</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/0363546514528093" target="_blank" >10.1177/0363546514528093</a>
Alternative languages
Result language
angličtina
Original language name
Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture Two-Year Follow-up of a Prospective Randomized Trial
Original language description
Background: Randomized controlled trials studying the efficacy and safety of matrix-applied characterized autologous cultured chondrocytes (MACI) versus microfracture (MFX) for treating cartilage defects are limited. Purpose: To compare the clinical efficacy and safety of MACI versus MFX in the treatment of patients with symptomatic cartilage defects of the knee. Study Design: Randomized controlled clinical trial; Level of evidence, 1. Methods: Patients enrolled in the SUMMIT (Demonstrate the Superiority of MACI implant to Microfracture Treatment) trial had >= 1 symptomatic focal cartilage defect (Outerbridge grade III or IV; >= 3 cm(2)) of the femoral condyles or trochlea, with a baseline Knee Injury and Osteoarthritis Outcome Score (KOOS) painvalue <55. The co-primary efficacy endpoint was the change in the KOOS pain and function subscores from baseline to 2 years.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FI - Traumatology and orthopaedics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The American Journal of Sports Medicine
ISSN
0363-5465
e-ISSN
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Volume of the periodical
42
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
1384-1394
UT code for WoS article
000340721400023
EID of the result in the Scopus database
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