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BCG vaccination in patients with severe combined immunodeficiency: Complications, risks, and vaccination policies

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077681" target="_blank" >RIV/00216224:14110/14:00077681 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/14:10292786 RIV/00159816:_____/14:00061366 RIV/00064203:_____/14:10292786

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.jaci.2014.02.028" target="_blank" >http://dx.doi.org/10.1016/j.jaci.2014.02.028</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jaci.2014.02.028" target="_blank" >10.1016/j.jaci.2014.02.028</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    BCG vaccination in patients with severe combined immunodeficiency: Complications, risks, and vaccination policies

  • Original language description

    Background: Severe combined immunodeficiency (SCID) is a syndrome characterized by profound T-cell deficiency. BCG vaccine is contraindicated in patients with SCID. Because most countries encourage BCG vaccination at birth, a high percentage of patientswith SCID are vaccinated before their immune defect is detected. Objectives: We sought to describe the complications and risks associated with BCG vaccination in patients with SCID. Methods: An extensive standardized questionnaire evaluating complications, therapeutics, and outcomes regarding BCG vaccination in patients given a diagnosis of SCID was widely distributed. Summary statistics and association analysis was performed. Results: Data on 349 BCG-vaccinated patients with SCID from 28 centers in 17countries were analyzed. Fifty-one percent of the patients had BCG-associated complications, 34% disseminated and 17% localized (a 33,000- and 400-fold increase, respectively, over the general population).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EC - Immunology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of allergy and clinical immunology

  • ISSN

    0091-6749

  • e-ISSN

  • Volume of the periodical

    133

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    1134-1141

  • UT code for WoS article

    000333531700025

  • EID of the result in the Scopus database