Influence of nanograin size of ZrO2 and Al2O3 ceramics on biological response of cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00077996" target="_blank" >RIV/00216224:14110/14:00077996 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.4028/www.scientific.net/KEM.587.132" target="_blank" >http://dx.doi.org/10.4028/www.scientific.net/KEM.587.132</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4028/www.scientific.net/KEM.587.132" target="_blank" >10.4028/www.scientific.net/KEM.587.132</a>

Result language
angličtina
Original language name
Influence of nanograin size of ZrO2 and Al2O3 ceramics on biological response of cells
Original language description
The influence of the grain size of alumina and zirconia ceramics on the spreading and adhesion of MG63 cell lines was investigated. Single-component ceramics and layered composite ceramics were prepared by electrophoretic deposition, uniaxial pressing and sintering. The grain size of zirconia was 100 urn to 2.7 mu m and that of alumina was 0.5 mu m to 1.5 mu m. Subsequently, sample surfaces were polished and thermally etched. Biological tests of adhesion (0.5 to 8 h) were used to evaluate the influenceof grain size on biological response. The highest cell spreading and adhesion was obtained for ZrO2 ceramics with an average grain size of 100 and 120 nm. The cell selection was observed on layered ZrO2/Al2O3 composites. The cells predominantly adhered to ZrO2 layers. The results showed a positive influence of nanostructured ceramic surfaces on biological behaviour of MG63 cells.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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