Fractional Flow Reserve-Guided PCI for Stable Coronary Artery Disease

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00078384" target="_blank" >RIV/00216224:14110/14:00078384 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/14:00061772
Result on the web
<a href="http://dx.doi.org/10.1056/NEJMoa1408758" target="_blank" >http://dx.doi.org/10.1056/NEJMoa1408758</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1056/NEJMoa1408758" target="_blank" >10.1056/NEJMoa1408758</a>

Result language
angličtina
Original language name
Fractional Flow Reserve-Guided PCI for Stable Coronary Artery Disease
Original language description
BACKGROUND We hypothesized that in patients with stable coronary artery disease and stenosis, percutaneous coronary intervention (PCI) performed on the basis of the fractional flow reserve (FFR) would be superior to medical therapy. METHODS In 1220 patients with stable coronary artery disease, we assessed the FFR in all stenoses that were visible on angiography. Patients who had at least one stenosis with an FFR of 0.80 or less were randomly assigned to undergo FFR-guided PCI plus medical therapy or toreceive medical therapy alone. Patients in whom all stenoses had an FFR of more than 0.80 received medical therapy alone and were included in a registry. The primary end point was a composite of death from any cause, nonfatal myocardial infarction, or urgent revascularization within 2 years. RESULTS The rate of the primary end point was significantly lower in the PCI group than in the medical-therapy group (8.1% vs. 19.5%; hazard ratio, 0.39; 95% confidence interval [CI], 0.26 to 0.57; P
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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