Diagnostic and Prognostic Utility of Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Patients with Cardiovascular Diseases - Review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00078559" target="_blank" >RIV/00216224:14110/14:00078559 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/14:00061629 RIV/65269705:_____/14:00061629
Result on the web
<a href="http://dx.doi.org/10.1159/000368474" target="_blank" >http://dx.doi.org/10.1159/000368474</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000368474" target="_blank" >10.1159/000368474</a>
Alternative languages
Result language
angličtina
Original language name
Diagnostic and Prognostic Utility of Neutrophil Gelatinase-Associated Lipocalin (NGAL) in Patients with Cardiovascular Diseases - Review
Original language description
NGAL (neutrophil gelatinase-associated lipocalin) is an acute phase protein, participating in antibacterial immunity. NGAL forms a complex with metalloproteinase 9 (MMP-9), thereby increasing its activity and preventing its degradation. NGAL is freely filtered through the glomerular membrane and reabsorbed by endocytosis in the proximal tubule. NGAL detected in urine is produced mainly in the distal nephron. Elevated serum and urine NGAL allows diagnosis of acute kidney injury approximately 24 hours earlier than plasma creatinine concentration. Increased levels of NGAL were detected in patients with acute myocardial infarction, heart failure or stroke and were demonstrated to be strong predictors of adverse prognosis.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Kidney and Blood Pressure Research
ISSN
1420-4096
e-ISSN
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Volume of the periodical
39
Issue of the periodical within the volume
6
Country of publishing house
CH - SWITZERLAND
Number of pages
7
Pages from-to
623-629
UT code for WoS article
000347728100013
EID of the result in the Scopus database
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