Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F14%3A00080091" target="_blank" >RIV/00216224:14110/14:00080091 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/j.jcyt.2013.09.008" target="_blank" >http://dx.doi.org/10.1016/j.jcyt.2013.09.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcyt.2013.09.008" target="_blank" >10.1016/j.jcyt.2013.09.008</a>

Result language

angličtina

Original language name

Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines

Original language description

Tumor growth is controlled by natural antitumor immune responses alone or by augmented immune reactivity resulting from different forms of immunotherapy, which has demonstrated clinical benefit in numerous studies, although the overall percentage of patients with durable clinical responses remains limited. This is attributed to the heterogeneity of the disease, the inclusion of late-stage patients with no other treatment options and advanced tumor-associated immunosuppression, which may be consolidatedby certain types of chemotherapy. Despite variable responsiveness to distinct types of immunotherapy, therapeutic cancer vaccination has shown meaningful efficacy for a variety of cancers. A key step during cancer vaccination involves the appropriate modeling of the functional state of dendritic cells (DCs) capable of co-delivering four critical signals for proper instruction of tumor antigen specific T cells.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cytotherapy

ISSN

1465-3249

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

13

Pages from-to

427-439

UT code for WoS article

000333438000002

EID of the result in the Scopus database

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