The miR-29 family in hematological malignancies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082058" target="_blank" >RIV/00216224:14110/15:00082058 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/15:00063089
Result on the web
<a href="http://dx.doi.org/10.5507/bp.2014.037" target="_blank" >http://dx.doi.org/10.5507/bp.2014.037</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2014.037" target="_blank" >10.5507/bp.2014.037</a>

Result language
angličtina
Original language name
The miR-29 family in hematological malignancies
Original language description
Background. MicroRNAs are short non-coding regulators of gene expression. The human miR-29 family consists of three members: miR-29a, miR-29b and miR-29c. Members of this family were found to be aberrantly expressed in various types of tumors, includinghematological malignancies. This family was described to have both oncogenic and tumor suppressor features influencing various pathological processes, such as tumor growth and apoptosis. This review summarizes current knowledge about the miR-29 family inselected hematological malignancies. Conclusion. Recent research of miR-29 family in hematological malignancies has proven its oncogenic as well as tumor suppressive potential. Nevertheless, the level of current evidence is not sufficient, and data remain inconclusive.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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