Small-nerve-fiber pathology in critical illness documented by serial skin biopsies

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082172" target="_blank" >RIV/00216224:14110/15:00082172 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/15:00063122

Result on the web

<a href="http://dx.doi.org/10.1002/mus.24489" target="_blank" >http://dx.doi.org/10.1002/mus.24489</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/mus.24489" target="_blank" >10.1002/mus.24489</a>

Result language

angličtina

Original language name

Small-nerve-fiber pathology in critical illness documented by serial skin biopsies

Original language description

Introduction: Small fiber pathology can develop in the acute phase of critical illness and may explain chronic sensory impairment and pain in critical care survivors. Methods: Eleven adult ischemic stroke patients in a neurocritical care unit were enrolled in an observational cohort study. Intraepidermal never fiber density (IENFD) in the distal leg was assessed on admission to the intensive care unit and 10-14 days later, together with electrophysiological testing. Results: Of the 11 patients recruited, 9 (82%) had sepsis or multiple organ failure. Median IENFD on admission (5.05 fibers/mm) decreased significantly to 2.18 fibers/mm (P &lt;0.001), and abnormal IENFD was found in 8 patients (72.7%). Electrodiagnostic signs of large fiber neuropathy and/or myopathy were found in 6 patients (54.5%), and autonomic dysfunction was found in 2 patients (18.2%). Discussion: Serial IENFD measurements confirmed the development of small fiber sensory involvement in the acute phase of critical ill

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Muscle & nerve

ISSN

0148-639X

e-ISSN

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Volume of the periodical

52

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

28-33

UT code for WoS article

000356498000005

EID of the result in the Scopus database

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