Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082786" target="_blank" >RIV/00216224:14110/15:00082786 - isvavai.cz</a>
Alternative codes found
RIV/61988987:17110/15:A1601FXH RIV/00216208:11110/15:10296542 RIV/65269705:_____/15:00063093
Result on the web
<a href="http://dx.doi.org/10.5507/bp.2015.014" target="_blank" >http://dx.doi.org/10.5507/bp.2015.014</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2015.014" target="_blank" >10.5507/bp.2015.014</a>
Alternative languages
Result language
angličtina
Original language name
Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data
Original language description
Background. Multiple myeloma (MM) is characterized by malignant proliferation of plasma cells (PC) which accumulate in the bone marrow (BM). The advent of new drugs has changed the course of the disease from incurable to treatable, but most patients eventually relapse. One group of MM patients (10-15%) is considered high-risk because they relapse within 24 months. Recently, extramedullary relapse of MM (EM) has been observed more frequently. Due to its aggressivity and shorter survival, EM is also considered high-risk. Aims. The goal of this study was to determine if the so-called high-risk genes published by the University of Arkansas group (UAMS) are even more deregulated in EM patients than in high-risk MM patients and if these patients may be considered high-risk. Methods. Nine samples of bone marrow plasma cells from MM patients as well as 9 tumors and 9 bone marrow plasma cells from EM patients were used.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic
ISSN
1213-8118
e-ISSN
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Volume of the periodical
159
Issue of the periodical within the volume
2
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
288-293
UT code for WoS article
000359128900020
EID of the result in the Scopus database
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