Increasing procoagulant activity of circulating microparticles in patients with Philadelphia-negative myeloproliferative neoplasms: a single-centre experience
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083018" target="_blank" >RIV/00216224:14110/15:00083018 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/15:00063096
Result on the web
<a href="http://dx.doi.org/10.1097/MBC.0000000000000293" target="_blank" >http://dx.doi.org/10.1097/MBC.0000000000000293</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/MBC.0000000000000293" target="_blank" >10.1097/MBC.0000000000000293</a>
Alternative languages
Result language
angličtina
Original language name
Increasing procoagulant activity of circulating microparticles in patients with Philadelphia-negative myeloproliferative neoplasms: a single-centre experience
Original language description
Microparticles are small membrane fragments with dimension between 0.1 and 1 mu m, which are released during cell activation or apoptosis, exposing the phospholipid phosphatidylserine and membrane antigens typical for cellular origin. Philadelphia-negative myeloproliferative neoplasms (MPNs) are characterized by an increased risk of thrombosis. Data from literature suggest an association between thrombosis and the procoagulant activity of microparticles. Association between the procoagulant activity ofmicroparticles and the incidence of thrombosis was assesed in a group of 126 patients with Philadelphia-negative MPNs. Measurement of microparticles procoagulant activity was performed using a functional assay, namely the Zymuphen MP-activity (Hyphen Biomed, Neuville-sur-oise, France). A total of 539 samples were analysed within this group of patients, regardless of patients' state of health.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BLOOD COAGULATION & FIBRINOLYSIS
ISSN
0957-5235
e-ISSN
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Volume of the periodical
26
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
448-453
UT code for WoS article
000353828800016
EID of the result in the Scopus database
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