Sex differences in the reinstatement of methamphetamine seeking after forced abstinence in Sprague-Dawley rats

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083330" target="_blank" >RIV/00216224:14110/15:00083330 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.3389/fpsyt.2015.00091" target="_blank" >http://dx.doi.org/10.3389/fpsyt.2015.00091</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fpsyt.2015.00091" target="_blank" >10.3389/fpsyt.2015.00091</a>

Result language

angličtina

Original language name

Sex differences in the reinstatement of methamphetamine seeking after forced abstinence in Sprague-Dawley rats

Original language description

Preventing relapse to drug abuse is one of the struggles faced by clinicians in order to treat patients with substance use disorders (DSM-5). There is a large body of clinical evidence suggesting differential characteristics of the disorder in men and women, which is in line with preclinical findings as well. The aim of this study was to assess differences in relapse-like behavior in methamphetamine (METH) seeking after a period of forced abstinence, which simulates the real clinical situation very well. Findings from such study might add new insights in gender differences in relapse mechanisms to previous studies, which employ a classical drug or cue-induced reinstatement procedure following the extinction training. Adult male and female Sprague-Dawley rats were used in IV self-administration procedure conducted in operant boxes using nose-poke operandi (Coulborn Instruments, USA). Active nose-poke resulted in activation of the infusion pump to deliver one intravenous infusion of METH

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Frontiers in Psychiatry

ISSN

1664-0640

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

91

Country of publishing house

CH - SWITZERLAND

Number of pages

8

Pages from-to

1-8

UT code for WoS article

000364467900001

EID of the result in the Scopus database

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