Long-term treatment for hyperphenylalaninemia and phenylketonuria: a risk for nutritional vitamin B12 deficiency?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083548" target="_blank" >RIV/00216224:14110/15:00083548 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/15:00063753
Result on the web
<a href="http://dx.doi.org/10.1515/jpem-2014-0489" target="_blank" >http://dx.doi.org/10.1515/jpem-2014-0489</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/jpem-2014-0489" target="_blank" >10.1515/jpem-2014-0489</a>
Alternative languages
Result language
angličtina
Original language name
Long-term treatment for hyperphenylalaninemia and phenylketonuria: a risk for nutritional vitamin B12 deficiency?
Original language description
Purpose: The objective of the study was to determine the incidence of vitamin B12 deficiency in patients under longterm treatment for phenylketonuria (PKU) and hyperphenylalaninemia (HPA), as well as its associations with B12 vitamin parameters (holotranscobalamin ? active vitamin B12, serum folate, total plasma homocysteine, and plasma methylmalonic acid concentration). Patients and methods: The group consisted of 51 PKU (n = 29) and HPA (n = 22) patients aged 3?48 years (28 children, 23 adults). Results: A significant difference in serum folate levels was discovered between adult HPA patients and PKU patients (p = 0.004, Mann-Whitney U-test). A significant difference in plasma homocysteine concentrations within the normal levels (p = 0.032, chi2-test) was detected between adult HPA and PKU patients.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FG - Paediatrics
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Pediatric Endocrinology and Metabolism
ISSN
0334-018X
e-ISSN
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Volume of the periodical
28
Issue of the periodical within the volume
11-12
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
1327-1332
UT code for WoS article
000365044600019
EID of the result in the Scopus database
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