Alcohol Consumption at Midlife and Risk of Stroke During 43 Years of Follow-Up Cohort and Twin Analyses
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083804" target="_blank" >RIV/00216224:14110/15:00083804 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/15:00061566
Result on the web
<a href="http://dx.doi.org/10.1161/STROKEAHA.114.006724" target="_blank" >http://dx.doi.org/10.1161/STROKEAHA.114.006724</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1161/STROKEAHA.114.006724" target="_blank" >10.1161/STROKEAHA.114.006724</a>
Alternative languages
Result language
angličtina
Original language name
Alcohol Consumption at Midlife and Risk of Stroke During 43 Years of Follow-Up Cohort and Twin Analyses
Original language description
Background and Purpose-Although alcohol-stroke association is well known, the age-varying effect of alcohol drinking at midlife on subsequent stroke risk across older adulthood has not been examined. The effect of genetic/early-life factors is also unknown. We used cohort and twin analyses of data with 43 years of follow-up for stroke incidence to help address these gaps. Methods-All 11 644 members of the population-based Swedish Twin Registry born 1886 to 1925 with alcohol data aged <= 60 years wereincluded. The interaction of midlife alcohol consumption by age at stroke was evaluated in Coxregression and analyses of monozygotic twins were used. Covariates were baseline age, sex, cardiovascular diseases, diabetes mellitus, stress reactivity, depression, body mass index, smoking, and exercise. Results-Altogether 29% participants developed stroke. Compared with very-light drinkers (<0.5 drink/d), heavy drinkers (>2 drinks/d) had greater risk of stroke (hazard ratio, 1.34; P=0.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Stroke
ISSN
0039-2499
e-ISSN
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Volume of the periodical
46
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
627-633
UT code for WoS article
000350284900017
EID of the result in the Scopus database
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