Hilar cholangiocarcinoma: palliation strategies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084677" target="_blank" >RIV/00216224:14110/15:00084677 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00270-015-1173-5" target="_blank" >http://dx.doi.org/10.1007/s00270-015-1173-5</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00270-015-1173-5" target="_blank" >10.1007/s00270-015-1173-5</a>
Alternative languages
Result language
angličtina
Original language name
Hilar cholangiocarcinoma: palliation strategies
Original language description
Tumours located in the hilar region often infiltrate early and encircle the vascular system (the branches of the common hepatic artery and portal vein), and cholangiocarcinomas also expand longitudinally into the intra- and extrahepatic bile ducts, submucosally and perineurially.The effect of systemic chemotherapy alone in the treatment of non-resectable cholangiocarcinomas is very limited. Stent implantation is an optimal solution for malignant obstructions in patients who are not candidates for surgical intervention and where the expected survival is longer than 3?6 months. IThe most frequent complication of SEMS is their closure. The stent gradually becomes covered with bile duct mucosa. In some patients, benign obstruction can occur due to its hyperplasia. Very frequently, stent occlusion is also associated with migration or closure by detritus and sludge formation. As disease progresses, there can occur ingrowth or overgrowth of the stent edge by the tumour.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů