Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00084697" target="_blank" >RIV/00216224:14110/15:00084697 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region
Original language description
Objective: To prove feasibility of percutaneous parallel implantation of partially covered, self-expandable metal stents (PC-SEMS) with antireflux valves (AR valves) in in-vivo model. Method: The novel design of PC-SEMS suitable for patients with hilar malignancies was developed. For percutaneous implantation of stent with AR valve, specific type of introducer is needed to prevent closing and crumpling of valve during implantation procedure. Stent is half covered with e-PTFE membrane, also forming AR valve. Proximal half of the stent is bare to allow flow of bile from segmental branches of biliary tree arising in hilar region. In-vivo experiment was chosen to test safe deployment of two PC-SEMS with AR valve. Parallel and synchronous implantation of stents was used in cross-bred piglet model. The procedure was performed under general anaesthesia with simulation of percutaneous approach. Open laparotomic view of duodenum was used for observation of AR valve.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů