Label-free and amplification-free miR-124 detection in human cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00085315" target="_blank" >RIV/00216224:14110/15:00085315 - isvavai.cz</a>
Alternative codes found
RIV/62156489:43210/15:43907632 RIV/00216305:26620/15:PU118479
Result on the web
<a href="http://dx.doi.org/10.3892/ijo.2014.2756" target="_blank" >http://dx.doi.org/10.3892/ijo.2014.2756</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3892/ijo.2014.2756" target="_blank" >10.3892/ijo.2014.2756</a>
Alternative languages
Result language
angličtina
Original language name
Label-free and amplification-free miR-124 detection in human cells
Original language description
MicroRNAs (miRNAs) are becoming a very important group of molecules especially since their connection to numerous diseases has been revealed. The potential in gene therapy as well as in diagnostics is being widely investigated leading to the demand of sensitive, selective and simple methods of isolation and detection. The combined advantages of magnetic particle-based separation with sensitive electrochemical detection may offer a very valuable tool for these purposes. In this study, the miR-124 was targeted as an example analyte for development and optimization of the isolation procedure coupled to the electrochemical detection. The sensitivity of the method was demonstrated by the limit of detection at the level of nanomolar concentration (4 nM).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP102%2F11%2F1068" target="_blank" >GAP102/11/1068: Nano-Electro-Bio-Tools for Biochemical and Molecularly-Biological Studies of Eukaryotic Cells (NanoBioTECell)</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Oncology
ISSN
1019-6439
e-ISSN
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Volume of the periodical
46
Issue of the periodical within the volume
2
Country of publishing house
GR - GREECE
Number of pages
7
Pages from-to
871-877
UT code for WoS article
000347671200049
EID of the result in the Scopus database
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