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Antineoplastic effects of Chlorella pyrenoidosa in the breast cancer model

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00085443" target="_blank" >RIV/00216224:14110/15:00085443 - isvavai.cz</a>

  • Alternative codes found

    RIV/00159816:_____/15:00063187

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.nut.2014.08.010" target="_blank" >http://dx.doi.org/10.1016/j.nut.2014.08.010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.nut.2014.08.010" target="_blank" >10.1016/j.nut.2014.08.010</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Antineoplastic effects of Chlorella pyrenoidosa in the breast cancer model

  • Original language description

    Objectives: There has been considerable interest in both clinical and preclinical research about the role of phytochemicals in the reduction of risk for cancer in humans. The aim of this study was to determine the antineoplastic effects of Chlorella pyrenoidosa in experimental breast cancer in vivo and in vitro. Methods: In this experiment, the antineoplastic effects of Chlorella pyrenoidosa in the chemoprevention of N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats were evaluated. Chlorella powder was administered through diet at concentrations of 0.3% and 3%. The experiment was terminated 14 wk after carcinogen administration. At autopsy, mammary tumors were removed and prepared for histopathological and immunohistochemical analysis. In vitro cytotoxicity assay, parameters of apoptosis, and proliferation after chlorella treatment in human breast adenocarcinoma (MCF-7) cells were carried out.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FM - Hygiene

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nutrition

  • ISSN

    0899-9007

  • e-ISSN

  • Volume of the periodical

    31

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    560-569

  • UT code for WoS article

    000351975200003

  • EID of the result in the Scopus database