Phenotypes of Escherichia coli isolated from urine: Differences between extended-spectrum beta-lactamase producers and sensitive strains

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00087433" target="_blank" >RIV/00216224:14110/15:00087433 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jmii.2014.04.010" target="_blank" >http://dx.doi.org/10.1016/j.jmii.2014.04.010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jmii.2014.04.010" target="_blank" >10.1016/j.jmii.2014.04.010</a>

Result language
angličtina
Original language name
Phenotypes of Escherichia coli isolated from urine: Differences between extended-spectrum beta-lactamase producers and sensitive strains
Original language description
Background: Escherichia coli is a frequent causative agent of urinary tract infections, and increasing resistance of Escherichia coli to antimicrobials presents a growing challenge. Methods: Here we compare phenotypes of extended-spectrum beta-lactamase (ESBL) producers (n = 220) with a control group of sensitive strains (non-ESBL producers; n = 150). For each strain, we assessed the presence of O25 antigen, hemolysis, biofilm production, sensitivity to antibiotics, and biochemical profile. Results: Compared to the control group, ESBL producers were more frequently O25 positive (6.0% vs. 42.3%) and less frequently hemolytic (34.7% vs. 6.4%). Comparison of biofilm production in brain-heart infusion (BHI) and in BHI with 4% glucose supplementation showed that ESBL-positive strains produced biofilm in BHI with glucose less intensely than the control group (p < 0.05). Most ESBL producers were ciprofloxacin-resistant (91.8%).
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/NS9665" target="_blank" >NS9665: Molecular typing of bacteriocins produced by strains of Escherichia coli isolated from clinical material: identification of colicin and microcin types among commensal and pathogenic strains</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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