Computer Analysis of Isolated Cardiomyocyte Contraction Process via Advanced Image Processing Techniques

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00087764" target="_blank" >RIV/00216224:14110/15:00087764 - isvavai.cz</a>
Alternative codes found
RIV/00159816:_____/16:00065845
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Computer Analysis of Isolated Cardiomyocyte Contraction Process via Advanced Image Processing Techniques
Original language description
Isolated cardiomyocytes (CMs) have been used as valid and useful model in experimental cardiology research for decades. A single CMs is considered as a functional unit with electrical, signaling, and mechanical functions of cell excitation-contraction process. The contraction function is usually measured via expensive and complex instruments which can either damage the cell or take much time for setting up Atomic Force Microscopy (AMF). In contrary, recent development of optical microscopy and digital cameras suggests utilization of touch-less CMs video acquisition in connection with advanced image processing techniques for automatic and precise evaluation of CMs contraction process. A typical adult CMs is a cylindrically-shaped cell (approx. with length 100µm and diameter 25µm) that can be observed as a bright structure surrounded by dark curve in bright-field optical microscopy. The dark curve surrounding the CMs are formed by cell membrane that blocks and scatters visible light.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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