Malignant catatonia due to anti-NMDA-receptor encephalitis in a 15-year-old girl: case report and summary of current knowledge

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F16%3A00091888" target="_blank" >RIV/00216224:14110/16:00091888 - isvavai.cz</a>

Result on the web

<a href="https://www.openaccessjournals.com/peer-review/malignant-catatonia-due-to-antinmdareceptor-encephalitis-in-a-15yearold-girl-case-report-and-summary-of-current-knowledge.html" target="_blank" >https://www.openaccessjournals.com/peer-review/malignant-catatonia-due-to-antinmdareceptor-encephalitis-in-a-15yearold-girl-case-report-and-summary-of-current-knowledge.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4172/Neuropsychiatry.1000132" target="_blank" >10.4172/Neuropsychiatry.1000132</a>

Result language

angličtina

Original language name

Malignant catatonia due to anti-NMDA-receptor encephalitis in a 15-year-old girl: case report and summary of current knowledge

Original language description

Anti-N-methyl-D-aspartate receptor encephalitis is a recently identified autoimmune disorder with a prominent neuropsychiatric presentation. We present the case of a 15-yearold girl with partial complex seizures with secondary generalization and acute mania with psychotic features. A positive diagnosis of anti-NMDA-receptor encephalitis suggested the specific treatment. Despite first-line immune treatment, the patient progressed to stupor, malignant catatonia, and autonomic instability with the risk of cardiopulmonary function failure. She improved after second-line immunosuppressive therapy (cyclophosphamide and rituximab simultaneously). Post-cognitive sequelae (memory impairment and deliberation) disappeared within 8 months of follow-up treatment and intensive cognitive rehabilitation. This case report emphasizes the importance of differential diagnosis and adequate treatment of catatonic syndrome, especially in young adults. Early recognition and adequate treatment is essential for a good outcome for the patients.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

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Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuropsychiatry

ISSN

1758-2008

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

136-141

UT code for WoS article

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EID of the result in the Scopus database

2-s2.0-85018520181