SOFT TISSUE METASTASIS OF MEDIASTINAL NON-FUNCTIONING PARAGANGLIOMA WITH UNUSUAL TTF-1 EXPRESSION: A POTENTIAL DIAGNOSTIC PITFALL
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F17%3A00104426" target="_blank" >RIV/00216224:14110/17:00104426 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.5114/pjp.2017.73931" target="_blank" >http://dx.doi.org/10.5114/pjp.2017.73931</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5114/pjp.2017.73931" target="_blank" >10.5114/pjp.2017.73931</a>
Alternative languages
Result language
angličtina
Original language name
SOFT TISSUE METASTASIS OF MEDIASTINAL NON-FUNCTIONING PARAGANGLIOMA WITH UNUSUAL TTF-1 EXPRESSION: A POTENTIAL DIAGNOSTIC PITFALL
Original language description
Metastatic extra-adrenal paragangliomas are very rare and can represent diagnostic challenges. We report a case of 69-year-old man with a tumor of the right shoulder. Histologic and immunohistochemical examinations confirmed the diagnosis of paraganglioma. Surprisingly, tumor cells were diffusely thyroid transcription factor 1 (TTF-1) positive. Succinate dehydrogenase complex subunit B (SDHB) deficiency has not been detected. Inherited syndromes associated with paragangliomas were ruled out. The primary tumor was identified in the mediastinum. This is the first report of TTF-1 expression in paraganglioma. To avoid misdiagnosis, careful clinical and pathological examination of any tumor with organoid growths pattern is necessary.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30109 - Pathology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
POLISH JOURNAL OF PATHOLOGY
ISSN
1233-9687
e-ISSN
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Volume of the periodical
68
Issue of the periodical within the volume
4
Country of publishing house
PL - POLAND
Number of pages
5
Pages from-to
354-358
UT code for WoS article
000428126800012
EID of the result in the Scopus database
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