Noninvasive Ventilatory Correction in Patients With Acute Ischemic Stroke A Systematic Review and Meta-Analysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F17%3A00113821" target="_blank" >RIV/00216224:14110/17:00113821 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/17:00067086

Result on the web

<a href="https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.017661" target="_blank" >https://www.ahajournals.org/doi/10.1161/STROKEAHA.117.017661</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1161/STROKEAHA.117.017661" target="_blank" >10.1161/STROKEAHA.117.017661</a>

Result language

angličtina

Original language name

Noninvasive Ventilatory Correction in Patients With Acute Ischemic Stroke A Systematic Review and Meta-Analysis

Original language description

Background and Purpose-Even though current guidelines suggest that noninvasive ventilatory correction (NIVC) could be considered for acute ischemic stroke patients with obstructive sleep apnea, available evidence is conflicting, with no adequately powered randomized clinical trial being available to date. Methods-We conducted a systematic review and meta-analysis of all available literature data evaluating the effect of NIVC on neurological improvement (based on decrease in National Institutes of Health Stroke Scale score), vascular events (recurrent stroke, transient ischemic attack, myocardial infarction and unstable angina), and mortality during the followup period. Results-We identified 4 randomized clinical trials and 1 prospectively matched observational cohort, comprising a total of 389 patients (59.8% males, mean age: 64.4 years). The risk of both performance and detection bias was considered high in most of the included randomized clinical trials because of the lack of blinding in participants, personnel and/ or outcome assessors. The mean decrease in National Institutes of Health Stroke Scale scores during the first (&lt;= 30) days of acute ischemic stroke was found to be greater in NIVC-treated patients in comparison to controls (standardized mean difference, 0.38; 95% confidence interval, 0.11-0.66; P= 0.007). However, no significant differences were detected between NIVC-treated acute ischemic stroke patients and controls on both the risk of vascular events (risk ratio, 0.53; 95% confidence interval, 0.25-1.14; P= 0.11) and mortality (risk ratio, 0.71; 95% confidence interval, 0.37-1.36; P= 0.30). No evidence of heterogeneity (I2= 0%; P for Cochran Q&gt; 0.50) or publication bias were detected in all analyses. Conclusions-NIVC seems to be associated with greater short-term neurological improvement in acute ischemic stroke patients with obstructive sleep apnea. This finding deserves further investigation within the settings of an adequately powered, sham-control, randomized clinical trial.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30210 - Clinical neurology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Stroke

ISSN

0039-2499

e-ISSN

—

Volume of the periodical

48

Issue of the periodical within the volume

8

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

2285-2288

UT code for WoS article

000406128300063

EID of the result in the Scopus database

2-s2.0-85020660809