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Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F17%3A00124678" target="_blank" >RIV/00216224:14110/17:00124678 - isvavai.cz</a>

  • Alternative codes found

    RIV/68081731:_____/17:00480387 RIV/00159816:_____/17:00066959 RIV/62157124:16370/17:43876013

  • Result on the web

    <a href="https://link.springer.com/article/10.1007/s00508-017-1176-0" target="_blank" >https://link.springer.com/article/10.1007/s00508-017-1176-0</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00508-017-1176-0" target="_blank" >10.1007/s00508-017-1176-0</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Respiratory induced heart rate variability during slow mechanical ventilation Marker to exclude brain death patients

  • Original language description

    Respiratory induced heart rate variability (rHRV) was analysed in mechanically ventilated patients during two levels of sedation and brain death. Our aim was to determine whether rHRV can distinguish between different levels of sedation and especially between brain death and sedated patients. In this study 30 critically ill and 23 brain death patients were included and four respiratory rates of 15, 12, 8 and 6 breaths per minute, each lasting 5 min were used. Two sedation levels, basal and deep, were performed in the critically ill patients. Heart rate and blood pressure changes induced by ventilation were subsequently detected and analysed. Significant differences were found in rHRV and rHRV adjusted for tidal volume (rHRV/VT) between critically ill and brain death patients during slow breathing at 6 or 8 breaths per minute. The rHRV at 6 breaths per minute was below 15 ms in all brain death subjects except one. The rHRV/VT was lower than 25 ms/l at both 6 and 8 breaths per minute in all brain death patients and simultaneously at 75% of non-brain death patients was higher (specificity 1, sensitivity 0.24). Differences in rHRV and rHRV/VTs between basal and deep sedation were not significant. The main clinical benefit of the study is the finding that rHRV and rHRV/VT during 6 and 8 breaths per minute can differentiate between critically ill and brain death patients. An rHRV/VT exceeding 25 ms/l reliably excludes brain death.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30218 - General and internal medicine

Result continuities

  • Project

    <a href="/en/project/GAP103%2F11%2F0933" target="_blank" >GAP103/11/0933: Analysis of EEG Signals Scanned at High Frequencies from Deep Brain Structures</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Wiener klinische Wochenschrift

  • ISSN

    0043-5325

  • e-ISSN

    1613-7671

  • Volume of the periodical

    129

  • Issue of the periodical within the volume

    7-8

  • Country of publishing house

    AT - AUSTRIA

  • Number of pages

    8

  • Pages from-to

    251-258

  • UT code for WoS article

    000399888100005

  • EID of the result in the Scopus database

    2-s2.0-85013778471