Telomere dynamics in adult hematological malignancies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F19%3A00108581" target="_blank" >RIV/00216224:14110/19:00108581 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/19:00070525
Result on the web
<a href="https://biomed.papers.upol.cz/pdfs/bio/2019/01/01.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2019/01/01.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2018.084" target="_blank" >10.5507/bp.2018.084</a>

Result language
angličtina
Original language name
Telomere dynamics in adult hematological malignancies
Original language description
Telomeres are repetitive DNA sequences protecting physical ends of linear chromosomes against degradation and endto- end chromosomal fusion. Telomeres shorten with each cell division, which regulates the cellular lifespan in somatic cells and limits their renewal capacity. Cancer cells are often able to overcome this physiological barrier and become immortal with unlimited replicative capacity. In this review, we present current knowledge on the role of telomeres in human aging with a focus on their behavior in hematological malignancies of adults. Associations of telomere length to age-related diseases and to the prevention of telomere shortening are also discussed.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10606 - Microbiology

Project
<a href="/en/project/NV15-31834A" target="_blank" >NV15-31834A: Selection of genomic defects in chronic lymphocytic leukemia and their impact on disease outcome</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)