Metabolic tricks of cancer cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F22%3A00125657" target="_blank" >RIV/00216224:14110/22:00125657 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/22:10445104
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0304419X22000300" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0304419X22000300</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bbcan.2022.188705" target="_blank" >10.1016/j.bbcan.2022.188705</a>
Alternative languages
Result language
angličtina
Original language name
Metabolic tricks of cancer cells
Original language description
One of the characteristics of cancer cells important for tumorigenesis is their metabolic plasticity. Indeed, in various stress conditions, cancer cells can reshape their metabolic pathways to support the increased energy request due to continuous growth and rapid proliferation. Moreover, selective pressures in the tumor microenvironment, such as hypoxia, acidosis, and competition for resources, force cancer cells to adapt by complete reorganization of their metabolism. In this review, we highlight the characteristics of cancer metabolism and discuss its clinical significance, since overcoming metabolic plasticity of cancer cells is a key objective of modern cancer therapeutics and a better understanding of metabolic reprogramming may lead to the identification of possible targets for cancer therapy.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
ISSN
0304-419X
e-ISSN
1879-2561
Volume of the periodical
1877
Issue of the periodical within the volume
3
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
18
Pages from-to
1-18
UT code for WoS article
000806557500001
EID of the result in the Scopus database
2-s2.0-85127536062