Influence of bacteriobilia on postoperative complications in patients with periampullary tumors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F23%3A00130476" target="_blank" >RIV/00216224:14110/23:00130476 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S1015958422011873" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1015958422011873</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.asjsur.2022.08.072" target="_blank" >10.1016/j.asjsur.2022.08.072</a>

Result language

angličtina

Original language name

Influence of bacteriobilia on postoperative complications in patients with periampullary tumors

Original language description

Background Periampullary tumours (PAT) may cause obstruction of distal choledochus. The bile stasis is a risk factor for microbial colonisation of bile (bacteriobilia), cholangitis, hepatic insufficiency and coagulopathy. PAT obstruction can be managed surgically or non-operatively - by inserting a biliary drain or stent (BDS). Although BDS allows for adequate bile drainage, liver function restitution and coagulopathy, increased bacteriobilia has been reported and this is associated with an increased incidence of postoperative complications. Methods A monocentric, prospective, comparative study including 100 patients operated with PAT. The effects of bacteriobilia and the presence of a drain in the biliary tract on the development of postoperative complications were evaluated. Results Positive microbial findings in bile were found in 67% of patients. It was 98% in the biliary drain group vs. 36% in non-drained patients (p = 0.0001). In 68% 2 or more different bacterial strains were simultaneously present (p = 0.0001). Patients with a positive microbial finding in bile had more frequent incidence of infectious complications 40.2% (27) vs. 9.1% (3); p = 0.0011. The most frequent infectious complication was wound infection 29.8% (20) vs. 3.03% (1); p = 0.0014. Similarly, a higher incidence of postoperative infectious complications occurred in patients with BDS - 36% (18) vs. 24% (12); p = 0.2752. Conclusion The presence of a drain or stent in the biliary tract significantly increases the microbial colonisation of bile. It is associated with a significant increase in infectious complications, especially infections in the wound.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30212 - Surgery

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Asian Journal of Surgery

ISSN

1015-9584

e-ISSN

0219-3108

Volume of the periodical

46

Issue of the periodical within the volume

3

Country of publishing house

SG - SINGAPORE

Number of pages

6

Pages from-to

1193-1198

UT code for WoS article

000953399000001

EID of the result in the Scopus database

2-s2.0-85137635036