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Influence of bacteriobilia on postoperative complications in patients with periampullary tumors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F23%3A00130476" target="_blank" >RIV/00216224:14110/23:00130476 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/pii/S1015958422011873" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1015958422011873</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.asjsur.2022.08.072" target="_blank" >10.1016/j.asjsur.2022.08.072</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Influence of bacteriobilia on postoperative complications in patients with periampullary tumors

  • Original language description

    Background Periampullary tumours (PAT) may cause obstruction of distal choledochus. The bile stasis is a risk factor for microbial colonisation of bile (bacteriobilia), cholangitis, hepatic insufficiency and coagulopathy. PAT obstruction can be managed surgically or non-operatively - by inserting a biliary drain or stent (BDS). Although BDS allows for adequate bile drainage, liver function restitution and coagulopathy, increased bacteriobilia has been reported and this is associated with an increased incidence of postoperative complications. Methods A monocentric, prospective, comparative study including 100 patients operated with PAT. The effects of bacteriobilia and the presence of a drain in the biliary tract on the development of postoperative complications were evaluated. Results Positive microbial findings in bile were found in 67% of patients. It was 98% in the biliary drain group vs. 36% in non-drained patients (p = 0.0001). In 68% 2 or more different bacterial strains were simultaneously present (p = 0.0001). Patients with a positive microbial finding in bile had more frequent incidence of infectious complications 40.2% (27) vs. 9.1% (3); p = 0.0011. The most frequent infectious complication was wound infection 29.8% (20) vs. 3.03% (1); p = 0.0014. Similarly, a higher incidence of postoperative infectious complications occurred in patients with BDS - 36% (18) vs. 24% (12); p = 0.2752. Conclusion The presence of a drain or stent in the biliary tract significantly increases the microbial colonisation of bile. It is associated with a significant increase in infectious complications, especially infections in the wound.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30212 - Surgery

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Asian Journal of Surgery

  • ISSN

    1015-9584

  • e-ISSN

    0219-3108

  • Volume of the periodical

    46

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    SG - SINGAPORE

  • Number of pages

    6

  • Pages from-to

    1193-1198

  • UT code for WoS article

    000953399000001

  • EID of the result in the Scopus database

    2-s2.0-85137635036