Ever-growing rodent teeth: Model system for studying stem cell niche, regeneration and repair

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F23%3A00139772" target="_blank" >RIV/00216224:14110/23:00139772 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Ever-growing rodent teeth: Model system for studying stem cell niche, regeneration and repair
Original language description
Continuously growing teeth are an amazing evolutionary adaptation that ensures the permanent regeneration of worn dental tissues. They also provide an attractive model system for studying stem cell niche, cell differentiation, regeneration, or activation of reparative mechanisms induced by injury. Using single-cell RNA-sequencing or lineage-tracing methods, we have identified novel aspects of stem cell niche behavior and complex cellular hierarchy in this renewing organ. The results of this work show the complexity, adaptability, and robustness of the stem cell niche and open new possibilities in the field of regenerative medicine.
Czech name
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Czech description
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Project
<a href="/en/project/GA22-02794S" target="_blank" >GA22-02794S: Mechanosensing as a mechanism controlling odontogenesis across vertebrates</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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