Vitamin D supplementation in cancer prevention and the management of cancer therapy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F24%3A00137798" target="_blank" >RIV/00216224:14110/24:00137798 - isvavai.cz</a>
Result on the web
<a href="https://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=8394&category_id=196&option=com_virtuemart" target="_blank" >https://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=8394&category_id=196&option=com_virtuemart</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/neo_2024_240531N240" target="_blank" >10.4149/neo_2024_240531N240</a>
Alternative languages
Result language
angličtina
Original language name
Vitamin D supplementation in cancer prevention and the management of cancer therapy
Original language description
Vitamin D is an important steroid hormone that exerts immunomodulatory actions, controls calcium and phosphate homeostasis, and significantly affects human health. Vitamin D deficiency is a global health problem, affecting approximately 60% of adults worldwide, and has been implicated in a range of different types of diseases, e.g., cancer. Vitamin D is involved in the regulation of cell proliferation, differentiation, energetic metabolism, and different types of cell death (e.g., apoptosis, autophagy, etc.). In physiological conditions, it is also able to modulate immune responses, angiogenesis, etc., which belongs to fundamental cancer-related processes. Vitamin D deficiency has been associated with an increased risk of some types of cancer, e.g., colorectal, breast, ovarian, prostate, pancreatic, etc. The role of vitamin D in cancer prevention, carcinogenesis, and cancer treatment is still under investigation and depends on the type of cancer. This review summarizes the role of vitamin D in all three above-mentioned aspects and discusses the mechanism of action and potential possibilities in cancer treatment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neoplasma
ISSN
0028-2685
e-ISSN
1338-4317
Volume of the periodical
71
Issue of the periodical within the volume
4
Country of publishing house
SK - SLOVAKIA
Number of pages
12
Pages from-to
307-318
UT code for WoS article
001335526400001
EID of the result in the Scopus database
2-s2.0-85204167157