Cathelicidins as antibacterial and antibiofilm agents against multidrug-resistant Pseudomonas aeruginosa
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F25%3A00144735" target="_blank" >RIV/00216224:14110/25:00144735 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Cathelicidins as antibacterial and antibiofilm agents against multidrug-resistant Pseudomonas aeruginosa
Original language description
Pseudomonas aeruginosa is a multidrug-resistant pathogen requiring alternative therapies. This study evaluated antibacterial and antibiofilm effects of five cathelicidins, naturally occurring antimicrobial peptides, and their combinations against 19 clinical strains. All tested strains were susceptible to at least one cathelicidin. The LL-37/SMAP-29 combination exhibited the strongest synergistic effect.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
<a href="/en/project/NU22-05-00475" target="_blank" >NU22-05-00475: Treatment of Infections Caused by Multidrug-Resistant Bacterial Strains by Novel Antibacterial Preparations Based on Cathelicidin Antimicrobial Peptides</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů