Effects of novel hydroxamic acids on cell cycle progression and cytodifferentiation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F22%3A00129762" target="_blank" >RIV/00216224:14160/22:00129762 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effects of novel hydroxamic acids on cell cycle progression and cytodifferentiation
Original language description
At the Department of Chemical Drugs of the Pharmaceutical Faculty, Masaryk University, a new group of hydroxamic acids was designed and synthesized based on similarity to the structure of vorinostat. The aim of the project was to evaluate the effects of selected new hydroxamic acids on the processes of cell cycle progression and cytodifferentiation in the monocytic leukemia cell line and to compare these effects with the activity of a reference substance, vorinostat.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů