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Stability of thymol self-emulsifying chitosan pellets for the potential treatment of intestinal mucosa

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F23%3A00134100" target="_blank" >RIV/00216224:14160/23:00134100 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Stability of thymol self-emulsifying chitosan pellets for the potential treatment of intestinal mucosa

  • Original language description

    The aim of the presented experimental study was to determine the stability of the Eugragit®L-coated chitosan/ Neusilin®US2 pellets containing thymol SEDDS. The first results confirmed the stability of uncoated self-emulsifying pellets with thymol in a half-year stability study in both storage conditions. On the contrary, the enteric-coated pellet formulation was stable only in the condition 25 °C/ 60 RH. Moreover, a mild deterioration of dissolution characteristics was reported.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30104 - Pharmacology and pharmacy

Result continuities

  • Project

    <a href="/en/project/GA22-03187S" target="_blank" >GA22-03187S: Rational Design of Polysaccharide‐based Particulate Systems for the Delivery of Mucosal Therapeutics with Broad Spectrum of Biological Activities</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů