Hydrogel solid self-emulsifying systems containing a thymol for targeting the distal parts of the GIT
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14160%2F23%3A00134101" target="_blank" >RIV/00216224:14160/23:00134101 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Hydrogel solid self-emulsifying systems containing a thymol for targeting the distal parts of the GIT
Original language description
he aim of this study was to prepare hydrogel particles based on two natural anionic polymers (sodium alginate and pectin) as a carrier of a thymol self-emulsifying system. Its control release could subsequently ensure a more balanced therapeutic concentration at the site of action. The calcium:zinc-crosslinked sample with 20% SES provided the most prolonged release of thymol. However, further in vitro and in vivo experiments are needed to assess further considerations regarding the appropriateness of administration in the IBD treatment.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/GA22-03187S" target="_blank" >GA22-03187S: Rational Design of Polysaccharide‐based Particulate Systems for the Delivery of Mucosal Therapeutics with Broad Spectrum of Biological Activities</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů