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PA-IIL like lectins: a common feature of high adaptability of some opportunistic bacteria

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F04%3A00010504" target="_blank" >RIV/00216224:14310/04:00010504 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    PA-IIL like lectins: a common feature of high adaptability of some opportunistic bacteria

  • Original language description

    Enormous potential of sugar structures gives them a crucial importance in recognition and signalling events. Carbohydrate-mediated recognition plays an important role in the ability of parasitic organisms to adhere to the surface of the host cell in thefirst step of their invasion and infectivity. For example, Pseudomonas aeruginosa galactose- and fucose-binding (PA-IL and PA-IIL) lectins contribute to the virulence of this pathogenic bacterium, which is a major cause of morbidity and mortality in cystic fibrosis patients [1]. Moreover, the PA-IIL lectin displays an affinity for fucose in micromolar range, unusually high for monosaccharide binding. Database searching in newly sequenced genomes revealed the presence of PA-IIL like proteins within someother opportunistic pathogens. Most of them comes from soil, are phylogenetically related and in past were usually considered as Pseudomonas spp. In addition to the pseudomonas lectin PA-IIL, we have been focused to its homologs coming fr

  • Czech name

    PA-IIL like lectins: společný znak vysoké adaptability některých podmíněných patogenů

  • Czech description

    PA-IIL like lectins: společný znak vysoké adaptability některých podmíněných patogenů

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LN00A016" target="_blank" >LN00A016: BIOMOLECULAR CENTER</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Acta Univ. Palacki. Olomouc., Fac. Rer. Nat., Chemica 43S

  • ISBN

    80-244-0353-6

  • ISSN

  • e-ISSN

  • Number of pages

    2

  • Pages from-to

    72-73

  • Publisher name

    Univerzita Palackého

  • Place of publication

    Olomouc

  • Event location

    Olomouc

  • Event date

    Jan 1, 2004

  • Type of event by nationality

    CST - Celostátní akce

  • UT code for WoS article