VALIDATION OF A CAPILLARY ZONE ELECTROPHORESIS METHOD FOR DETERMINATION OF RIMANTADINE HYDROCHLORIDE IN RIMANTADIN100 TABLETS AND THE METHOD APPLICATION TO DISSOLUTION TEST MONITORING
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F04%3A00010941" target="_blank" >RIV/00216224:14310/04:00010941 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
VALIDATION OF A CAPILLARY ZONE ELECTROPHORESIS METHOD FOR DETERMINATION OF RIMANTADINE HYDROCHLORIDE IN RIMANTADIN100 TABLETS AND THE METHOD APPLICATION TO DISSOLUTION TEST MONITORING
Original language description
A capillary zone electrophoretic method with indirect UV-detection for determination of rimantadine, an antiviral drug against influenza A, in tablets was validated. Instrumental precision, the method precision, accuracy, calibration curve linearity, selectivity, robustness and time stability of the sample and the standard were tested. The method was also applied to monitor dissolution tests of the tablets. The possibility of internal standard for improvement of method precision was discussed.
Czech name
VALIDACE METODY KAPILARNI ZONOVE ELEKTROFOREZY PRO STANOVENI RIMANTADIN HYDROCHLORIDU V TABLETACH RIMANTADIN100 A APLIKACE METODY NA DISOLUCNI TESTYN TEST MONITORING
Czech description
A capillary zone electrophoretic method with indirect UV-detection for determination of rimantadine, an antiviral drug against influenza A, in tablets was validated. Instrumental precision, the method precision, accuracy, calibration curve linearity, selectivity, robustness and time stability of the sample and the standard were tested. The method was also applied to monitor dissolution tests of the tablets. The possibility of internal standard for improvement of method precision was discussed.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
ISSN
0363-9045
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
125-134
UT code for WoS article
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EID of the result in the Scopus database
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