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An analysis of tissues of vertebrates treated by Bromadiolone

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F06%3A00015746" target="_blank" >RIV/00216224:14310/06:00015746 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    An analysis of tissues of vertebrates treated by Bromadiolone

  • Original language description

    Bromadiolone is a 4-hydroxy-coumarine derivative used as rodenticide, which shows an anticoagulant effect based on the prothrombine synthesis inhibition. The determination of this compound has interest in toxicological analysis owing to its high accute oral toxicity. The dose of bromadiolone, which is expected to cause death of 50 % of male rats by oral administration (LD50) is 1.125 mg.kg-1. A determination of this compound of interest has also interest in environmental analysis taking into account itswide use to control rodent populations, which involves the resulting risk of water pollution or intoxication of non-target species. Thus we focused on suggesting of a new technique for determination of bromadiolone using high-performance liquid chromatography with electrochemical detection (HPLC-ED). Prior to analysis in flow system we have studied the basic electrochemical behaviour of bromadiolone by cyclic voltammetry on Autolab analyser (EcoChemie, Netherlands) connected with VA-Sta

  • Czech name

    Analýza tkání z hrabošů krmených bromadiolonem

  • Czech description

    Analýza tkání z hrabošů krmených bromadiolonem

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Study of protection mechanisms for stress-induced by heavy metals</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Toxcon 2006; 11. Interdisciplinary Slovak - Czech Toxicological Conference

  • ISBN

    80-969474-1-9

  • ISSN

  • e-ISSN

  • Number of pages

    300

  • Pages from-to

    39-39

  • Publisher name

    Slovak Toxicology Society SETOX

  • Place of publication

    Trencianske Teplice

  • Event location

    Trencianske Teplice

  • Event date

    Jun 5, 2006

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article