Electrochemical study of S nitrosoglutathione and nitric oxide by carbon fibre NO sensor and cyclic voltammetry - possible way of monitoring of nitric oxide

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F06%3A00016157" target="_blank" >RIV/00216224:14310/06:00016157 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/06:00103373

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Electrochemical study of S nitrosoglutathione and nitric oxide by carbon fibre NO sensor and cyclic voltammetry - possible way of monitoring of nitric oxide

Original language description

Nitrosation of sulfhydryl group of glutathione, which is highly reactive and is often found conjugated to other molecules via its sulfhydryl moiety, is one of many biological effects of the nitric oxide (NO). This process may serve as a signal event and/or as a deposition of NO to S-nitrosoglutathione (GSNO). Moreover, GSNO may release NO under specific conditions. That is why NO, which has a little lifetime itself, could be distribute for longer distances within the organism. Here, we studied and compared the basic electrochemical characteristics of biological active thiol compounds (GSH, oxidized glutathione and GSNO). In addition, observation of the decomposition process of GSNO using different electrochemical techniques followed. Primarily we studied the influence of scan rate and reducing agent (Tris(2-carboxyethyl)phosphine). The CV calibration equations were linear, R.S.D. about 5%. The detection limits of GSH, GSSG and GSNO expressed as 3 S/N were 9 nM, 4 nM and 20 nM, respecti

Czech name

Elektrochemická studie Snitrosoglutathionu a oxidu dusného pomocí uhlíkového vlákna a cyklické voltametrie - možná cesta monitoringu NO

Czech description

Elektrochemická studie Snitrosoglutathionu a oxidu dusného pomocí uhlíkového vlákna a cyklické voltametrie - možná cesta monitoringu NO

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CG - Electrochemistry

OECD FORD branch

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Project

<a href="/en/project/GP525%2F04%2FP132" target="_blank" >GP525/04/P132: Study of protection mechanisms for stress-induced by heavy metals</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Electrochim. Acta

ISSN

0013-4686

e-ISSN

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Volume of the periodical

51

Issue of the periodical within the volume

24

Country of publishing house

GB - UNITED KINGDOM

Number of pages

5

Pages from-to

5087-5094

UT code for WoS article

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EID of the result in the Scopus database

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