The fibroblast growth factors in multiple myeloma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F06%3A00064401" target="_blank" >RIV/00216224:14310/06:00064401 - isvavai.cz</a>
Result on the web
<a href="http://www.nature.com/leu/journal/v20/n6/full/2404202a.html" target="_blank" >http://www.nature.com/leu/journal/v20/n6/full/2404202a.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/sj.leu.2404202" target="_blank" >10.1038/sj.leu.2404202</a>
Alternative languages
Result language
angličtina
Original language name
The fibroblast growth factors in multiple myeloma
Original language description
Fibroblast growth factor receptor 3 (FGFR3) is a membrane-anchored receptor tyrosine kinase that transmits intercellular signals mediated by a family of fibroblast growth factors (FGFs). In multiple myeloma (MM), 15% of patients markedly upregulate FGFR3as a consequence of a t(4;14)(p16.3;q32) translocation. Ectopic expression of FGFR3 enhances MM cell proliferation and survival, demonstrating the oncogenic potential of FGFR3.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Leukemia
ISSN
0887-6924
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
6
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
1165-1168
UT code for WoS article
000237806500038
EID of the result in the Scopus database
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