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Clinical implications of chromosomal aberrations (13q14 and 17p13 deletion, translocation t(4;14) and 1q21 amplification) in patients with relapsed multiple myeloma treated by thalidomide or bortezomib (Velcade)

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00019107" target="_blank" >RIV/00216224:14310/07:00019107 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Clinical implications of chromosomal aberrations (13q14 and 17p13 deletion, translocation t(4;14) and 1q21 amplification) in patients with relapsed multiple myeloma treated by thalidomide or bortezomib (Velcade)

  • Original language description

    The aim of the work was: 1) To study the incidence of the chromosomal aberrations known as adverse prognostic factors in MM - deletion of 13q14 (RB1), deletion of 17p13 (p53), amplification of 1q21 (CKS1B) and translocation t(4;14) in a group of 40 patients with relapsed MM. 2) To compare the prognostic and predictive significance of these unfavorable chromosomal aberrations in patients with relapsed MM treated with thalidomide or bortezomib (Velcade) based regimens.

  • Czech name

    Klinické důsledky výskytu chromozomálních aberací (delece 13q14 a 17p13, translokace t(4;14) a amplifikaci 1q21) u pacientů s mnohočetným myelomem léčených thalidomodem nebo bortezomibem (Velcade)

  • Czech description

    V práci je shrnutí našich současných poznatků o vlivu cytogenetických negativních prognostických markerů u nemocných mnohočetným myelomem léčených novými léky.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    From cell sorting to plasma cell identification and chromosomal aberrations in multiple myeloma ? Application manual

  • ISBN

    978-80-210-4417-3

  • ISSN

  • e-ISSN

  • Number of pages

    2

  • Pages from-to

    12-13

  • Publisher name

    vydavatelství Masarykovy Univerzity

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Oct 10, 2007

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article