Review: Application of capillary electrophoresis in drug metabolism studies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00020296" target="_blank" >RIV/00216224:14310/07:00020296 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Review: Application of capillary electrophoresis in drug metabolism studies
Original language description
Capillary electrophoresis (CE) has been increasingly employed for the separation of pharmaceutical agents and drugs. This has arisen from the complementary mode of separation afforded by CE when compared to high performance liquid chromatography (HPLC).Qualities of CE such as high efficiency of separation, short analysis time, remarkably low injection volume and a variety of detection systems have facilitated acceptance of this technology. Since different drug metabolite enantiomers are formed in manymetabolic pathways, the other indispensable advantage of CE over HPLC is the possibility of chiral separation without the need of special expensive columns. Recent advances in automated systems have made CE even more popular. The focus of this paper is to review recent studies and advances (mainly from 2000) of drug metabolism by using CE. The review is divided into two parts: (i) principles of CE separation of drugs and their metabolites and (ii) application of CE in drug metabolism stu
Czech name
Review: Využití kilární elektroforézy pro studium metabolismu léčiv
Czech description
Tento přehledný článek shrnuje problematiku využití CE pro studium metabolismu léčiv.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Analytical Chemistry
ISSN
1573-4110
e-ISSN
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Volume of the periodical
3
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
21
Pages from-to
197-217
UT code for WoS article
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EID of the result in the Scopus database
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