Coupling of microcolumn separations to MALDI MS

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00024581" target="_blank" >RIV/00216224:14310/07:00024581 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Coupling of microcolumn separations to MALDI MS
Original language description
Electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) are preferred ionization techniques in analysis of polymers. While ESI is usually chosen for on-line coupling of column separations to MS, MALDI is used for MS screening of large number of samples. Certain features of MALDI, however, make it more attractive in some applications: MALDI spectra, dominated by singly charged ions, are simpler and solid samples prepared on MALDI targets can be archived. This lecture will give an overview of approaches for coupling of microLC and CE with MALDI MS. The power of separation coupled a TOF/TOF instrument will be demonstrated on sensitive multidimensional analysis of complex biological samples. In conjunction with TOF mass spectrometer and high repetition rate lasers, extremely fast analyses can be achieved. The potential for high throughput MS analysis will be discussed on example of on-line and off-line analysis.
Czech name
Spojení mikrokolonových separací s MALDI MS
Czech description
Souhrnná přednáška o spojení mikrokolonových separačních technik s MALDI TOF MS

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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