Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F07%3A00035882" target="_blank" >RIV/00216224:14310/07:00035882 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors

Original language description

A series of four bicyclic cores were prepared and evaluated and cyclin-dependent kinase-2 (CDK2) inhibitors. From the in vitro and cell-based analysis, the pyrazolo[1,5-a]pyrimidine core (represented by 9) emerged as the superior for further elaborationin the identification of novel CDK2 inhibitors.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Bioorganic & Medicinal Chemistry Letters

ISSN

0960-894X

e-ISSN

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Volume of the periodical

2007

Issue of the periodical within the volume

17

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

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UT code for WoS article

000250906200035

EID of the result in the Scopus database

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