Construction of mutant lectins from Chromobacterium violaceum and study of changes in their binding properties
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F09%3A00042640" target="_blank" >RIV/00216224:14310/09:00042640 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Construction of mutant lectins from Chromobacterium violaceum and study of changes in their binding properties
Original language description
The aim of this work is in vitro creation of mutant lectins from oportunistic human pathogen Chromobacterium vioalceum. Substitution of amino acids in the lectin structure should lead to changes of lectin sugar specificity. Mutation were focused on the "specificity binding loop" in the position 22-23-24 and in other position 97. The work is going to be followed by structural and functional analysis.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LC06030" target="_blank" >LC06030: Biomolecular centre</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů