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Construction of mutant lectins from Chromobacterium violaceum and study of changes in their binding properties

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F09%3A00042640" target="_blank" >RIV/00216224:14310/09:00042640 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Construction of mutant lectins from Chromobacterium violaceum and study of changes in their binding properties

  • Original language description

    The aim of this work is in vitro creation of mutant lectins from oportunistic human pathogen Chromobacterium vioalceum. Substitution of amino acids in the lectin structure should lead to changes of lectin sugar specificity. Mutation were focused on the "specificity binding loop" in the position 22-23-24 and in other position 97. The work is going to be followed by structural and functional analysis.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LC06030" target="_blank" >LC06030: Biomolecular centre</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů