An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F10%3A00040768" target="_blank" >RIV/00216224:14310/10:00040768 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

An unusual loss of EGFR gene copy in glioblastoma multiforme in a child: a case report and analysis of a successfully derived HGG-02 cell line

Original language description

This study report on a case of glioblastoma multiforme with a polyploid karyotype including a very unusual genetic change - the loss of a copy of the EGFR gene at locus 7p11.2 (EGFR gene) - diagnosed in a 14.5-year-old boy. To date, this patient has survived event-free for 34 months. A detailed analysis of the HGG-02 cell line, which was derived from this primary tumor, was also performed.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/NR9125" target="_blank" >NR9125: Importance of molecular cytogenetic markers for diagnosis and prediction of embryonal childhood tumors.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Child's Nervous System

ISSN

0256-7040

e-ISSN

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Volume of the periodical

26

Issue of the periodical within the volume

6

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

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UT code for WoS article

000277595300022

EID of the result in the Scopus database

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